Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial

نویسندگان
چکیده

منابع مشابه

Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial

INTRODUCTION Observational evidence suggests physiological benefits and lower mortality with lower chloride solutions; however, 0.9% saline remains the most widely used fluid worldwide. Given uncertainty regarding the association of lower chloride on mortality, it is unlikely that practice will change without direct randomised clinical trial (RCT) evidence. This pilot RCT will investigate the f...

متن کامل

Early Fluid Resuscitation and High Volume Hemofiltration Decrease Septic Shock Progression in Swine

This study aimed to assess the effects of early fluid resuscitation (EFR) combined with high volume hemofiltration (HVHF) on the cardiopulmonary function and removal of inflammatory mediators in a septic shock swine model. Eighteen swine were randomized into three groups: control (n = 6) (extracorporeal circulating blood only), continuous renal replacement therapy (CRRT) (n = 6; ultrafiltration...

متن کامل

High-volume hemofiltration in septic shock

In the past decade we have learned a lot about the pathophysiology of septic shock. A lot of experimental research has been performed in vitro and in vivo, showing that hemofiltration can improve hemodynamics and survival. With modern machines, hemofiltration is becoming a sepsis treatment in patients.

متن کامل

Reply Fluid Resuscitation in Septic Shock

INDIAN PEDIATRICS 844 VOLUME 42__AUGUST 17, 2005 3. Argyropoulou MI, Metafratzi Z, Kiortsis DN, Bitsis S, Tsatsoulis A, Efremidis S. T2 relaxation rate as an index of pituitary iron overload in patients with beta-thalassemia major. AJR Am J Roentgenol. 2000; 175: 1567-1569. clinical practice because of cost and nonavailability. We concur with the views on pituitary MR imaging as an index of iro...

متن کامل

A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock

OBJECTIVE The Fluids in Shock (FiSh) Trial proposes to evaluate whether restrictive fluid bolus therapy (10 mL/kg) is more beneficial than current recommended practice (20 mL/kg) in the resuscitation of children with septic shock in the UK. This qualitative feasibility study aimed to explore acceptability of the FiSh Trial, including research without prior consent (RWPC), potential barriers to ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2018

ISSN: 0003-9888,1468-2044

DOI: 10.1136/archdischild-2018-314924